Artikel #:
0042-05
Antigen/Produkt:
alpha-Actinin 4
Synonym(e):
α-Actinin 4
Klon / Name:
IG-701
Aus Spezies:
Kaninchen
Mono-/polyklonal:
polyklonal (pAB) | epitop-selektiv
Reinheit:
affinitätsgereinigt am Antigen
Menge (Masse):
50 µg
Menge (Vol.):
200 µl
Preis (netto):
295.00 €
Reaktion mit Spezies:
Mensch, Maus, Ratte, Schwein
Anwendungen:
WB - Western Blot / Immunoblot, IF - Immunfluoreszenz, IHC - Immun-Histochemie, IP - Immunpräzipitation
Verdünnungen:
WB 1:2,500 | IF 1:250- 1:1,600 | IP 1:10
Getestete Fixierungen:
Formaldehyd
Form:
steril filtrierte Lösung, mit Na-Azid, stabilisiert mit Träger(protein)
Immunisierung:
Peptid
Epitop:
Peptid aus der Nähe des N-Terminus, das spezifisch ist für Isoform 4
Lagerung:
-20°C
Versand:
RT - ungekühlt
Verfügbarkeit:
vorrätig
Datenblatt:
Figure(s):
Publikationen, die dieses Produkt verwenden:
1.
Bhatnagar, A. et al. Interaction of G-protein βγ complex with chromatin modulates GPCR-dependent gene regulation. PLoS ONE 8, e52689 (2013). (Article).
2.
Jayadev, R., Kuk, C. Y., Low, S. H. & Murata-Hori, M. Calcium sensitivity of α-actinin is required for equatorial actin assembly during cytokinesis. Cell Cycle 11, 1929–1937 (2012). (Article).
3.
Meyer-Schwesinger, C. et al. Ubiquitin C-terminal hydrolase-l1 activity induces polyubiquitin accumulation in podocytes and increases proteinuria in rat membranous nephropathy. Am. J. Pathol. 178, 2044–2057 (2011). (Article).
4.
Meyer-Schwesinger, C. et al. Nephrotic Syndrome and Subepithelial Deposits in a Mouse Model of Immune-Mediated Anti-Podocyte Glomerulonephritis. J Immunol 187, 3218–3229 (2011). (Article).
5.
Hartleben, B. et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. Journal of Clinical Investigation 120, 1084–1096 (2010). (Article).
6.
Yang, C. & Glass, W. F. Expression of α-Actinin-1 in Human Glomerular Mesangial Cells In Vivo and In Vitro. Experimental Biology and Medicine 233, 689–693 (2008). (Article).
7.
Kimura, M. et al. Expression of alpha-actinin-4 in human diabetic nephropathy. Intern. Med. 47, 1099–1106 (2008). (Article).
8.
Mukhina, S., Wang, Y.-L. & Murata-Hori, M. Alpha-actinin is required for tightly regulated remodeling of the actin cortical network during cytokinesis. Dev. Cell 13, 554–565 (2007). (Article).
9.
Bolshakova, A. et al. Extra-cellular matrix proteins induce re-distribution of alpha-actinin-1 and alpha-actinin-4 in A431 cells. Cell Biol. Int. 31, 360–365 (2007). (Article).
10.
Galler, A. B. et al. VASP-dependent regulation of actin cytoskeleton rigidity, cell adhesion, and detachment. Histochem. Cell Biol. 125, 457–474 (2006). (Article).
11.
Bariety, J., Mandet, C., Hill, G. S. & Bruneval, P. Parietal Podocytes in Normal Human Glomeruli. JASN 17, 2770–2780 (2006). (Article).
12.
Iida, Y. & Chiba, H. The Relationship between Subcellular Localization of Actinin-4 and Cell Motility in Oral Squamous Cell Carcinoma. Oral Science International 1, 30–37 (2004). (Article).
13.
Goode, N. P., Shires, M., Khan, T. N. & Mooney, A. F. Expression of α-actinin-4 in acquired human nephrotic syndrome: a quantitative immunoelectron microscopy study. Nephrol. Dial. Transplant. 19, 844–851 (2004). (Article).
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