Artikel #:
0112-02
Antigen/Produkt:
NFATc2, NFATp, nuclear factor of activated T-cells
Synonym(e):
NFATc2
Uni-/SwissProt #:
Q60591, A2APK2, Q91Y65
Klon / Name:
IG-209
Aus Spezies:
Kaninchen
Mono-/polyklonal:
polyklonal (pAB) | anti-Gesamtprotein
Reinheit:
affinitätsgereinigt am Antigen
Menge (Masse):
20 µg
Menge (Vol.):
100 µl
Preis (netto):
320.00 €
Reaktion mit Spezies:
Mensch
Anwendungen:
WB - Western Blot / Immunoblot, IF - Immunfluoreszenz, IHC - Immun-Histochemie, IP - Immunpräzipitation, ChIP - Chromatin-Immunpräzipitation
Verdünnungen:
WB: (1:500); IF: (1:50); IP: (1:100); ChIP (1:100)
Getestete Fixierungen:
Formaldehyd
Form:
steril filtrierte Lösung, mit Na-Azid, stabilisiert mit Träger(protein)
Immunisierung:
rekombinantes Protein (Gesamtsequenz)
Lagerung:
-20°C
Versand:
Kühlpaket
Verfügbarkeit:
vorrätig
Datenblatt:
Publikationen, die dieses Produkt verwenden:
1.
Shaked, I. & Ley, K. Methods of Inhibiting Inflammation and Inflammatory Diseases Using Gal-3bp (btbd17b, Lgals3bp, Galectin-3 Binding Protein, Mac-2 Binding Protein). (2013) EP2566878 (A1).
2.
Patra, A. K. et al. An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development. Nat Immunol 14, 127–135 (2013). (Article).
3.
Vaeth, M. et al. Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells. Proc. Natl. Acad. Sci. U.S.A. 109, 16258–16263 (2012). (Article).
4.
Gerlach, K. et al. Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis. Cancer Res. 72, 4340–4350 (2012). (Article).
5.
Bhattacharyya, S. et al. NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network. J. Exp. Med. 208, 823–839 (2011). (Article).
6.
Radbruch, A. et al. Method for in-Vitro Detecting Pathogenic T Helper Cells and Pharmaceutical Compositions for Treating Autoimmune Diseases. (2010). EP2223107 (A1).
7.
Flach, H. et al. Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells. Immunity 33, 723–735 (2010). (Article).
8.
Zanoni, I. et al. CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation. Nature 460, 264–268 (2009). (Article).
9.
Ullerås, E. et al. NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells. Blood 111, 3081–3089 (2008). (Article).
10.
Niesner, U. et al. Autoregulation of Th1-mediated inflammation by twist1. J Exp Med 205, 1889–1901 (2008). (Article).
11.
Klein-Hessling, S. et al. Cyclic AMP-induced Chromatin Changes Support the NFATc-mediated Recruitment of GATA-3 to the Interleukin 5 Promoter. J. Biol. Chem. 283, 31030–31037 (2008). (Article).
12.
Akimzhanov, A. et al. Epigenetic Changes and Suppression of the Nuclear Factor of Activated T Cell 1 (NFATC1) Promoter in Human Lymphomas with Defects in Immunoreceptor Signaling. Am J Pathol 172, 215–224 (2008). (Article).
13.
Klein, M. et al. Specific and Redundant Roles for NFAT Transcription Factors in the Expression of Mast Cell-Derived Cytokines. J Immunol 177, 6667–6674 (2006). (Article).
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