Article #:
0032-05
Antigen/Product:
LPP - Lipoma Preferred Partner
Synonym(s):
LPP
Uni-/SwissProt #:
Q93052, A1L4L6, D3DNV6, Q8NFX5
Clone / Name:
IG-817
Host Species:
rabbit
Mono-/polyclonal:
polyclonal (pAB) | anti-(partial sequence)
Purity:
affinity purified on the antigen
Quantity (mass):
50 µg
Quantity (vol.):
100 µl
Price (net):
255.00 €
Cross-reactivity:
human, rat, pig
Applications:
WB - Western blot / immunoblot, IF - immunofluorescence, IP - immunoprecipitation
Sugg. dilutions:
WB 1:1,000 | IF 1:500 | IP (depending on assay system)
Fixatives tested:
formaldehyde
Form:
sterile filtered liquid, with sodium azide, carrier-free
Immunization:
recombinant protein (partial sequence)
Epitope:
The antibody was raised against a recombinant fusion protein comprising residues 1-109 of human LPP. Residual GST specific antibody activity is less than 5% of total activity (as assayed by immuno blotting)
Storage:
-20°C
Shipping:
RT - ambient temperature
Availability:
in stock
Data sheet:
Figure(s):
Publications referring to this product:
1.
Tondeleir, D. et al. Cells Lacking -Actin are Genetically Reprogrammed and Maintain Conditional Migratory Capacity. Molecular & Cellular Proteomics 11, 255–271 (2012). (Article).
2.
Mihlan, S. et al. Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions. Oncogene (2012). (Article).
3.
Colas, E. et al. ETV5 cooperates with LPP as a sensor of extracellular signals and promotes EMT in endometrial carcinomas. Oncogene 31, 4778–4788 (2012). (Article).
4.
Jin, L., Yoshida, T., Ho, R., Owens, G. K. & Somlyo, A. V. The Actin-associated Protein Palladin Is Required for Development of Normal Contractile Properties of Smooth Muscle Cells Derived from Embryoid Bodies. J. Biol. Chem. 284, 2121–2130 (2009). (Article).
5.
Jin, L., Hastings, N. E., Blackman, B. R. & Somlyo, A. V. Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury. Journal of Muscle Research and Cell Motility 30, 41–55 (2009). (Article).
6.
Jin, L., Kern, M. J., Otey, C. A., Wamhoff, B. R. & Somlyo, A. V. Angiotensin II, Focal Adhesion Kinase, and PRX1 Enhance Smooth Muscle Expression of Lipoma Preferred Partner and its Newly Identified Binding Partner Palladin to Promote Cell Migration. Circulation Research 100, 817–825 (2007). (Article).
7.
Gorenne, I. et al. LPP, a LIM protein highly expressed in smooth muscle. Am J Physiol Cell Physiol 285, C674–C685 (2003). (Article).
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