Custom Antibody Services for Special Applications

Antibodies against Cleavage Sites

Confocal microscopy
Custom-made: rb. anti-cleaved collagen 3/4 (green); b/w: intact collagen matrix; red: HT1080 cell

Custom-made antibodies that recognize a protein only when cleaved by a protease, but not in its native form (non-cleaved).

    Possible applications:
  • Caspase substrates
  • Tacking metastasing can­cer cells via trails of cleaved collagen that they leave behind

Antibodies against Phospho Sites

Western Blot
Custom-made: rb. anti-­phospho-­Ser146 LASP

Custom-made antibodies that recognize a protein only in its phos­phory­lated form or, vice versa, only in its non-phos­phory­lated form. Looking for antibodies that dis­criminate between any combination of phos­phory­lation states of di- or multi-phos­phory­lated proteins?

ABs against Point Mutations & Variants

3D model with mutation
Detect your mutated protein

In need of antibodies that recognize a protein only when mutated or otherwise modified? As few as one (1!) amino acid difference are sufficient to raise a highly specific rabbit antibody against your variant of interest!

 

Don't hesitate and ask for our proposal...

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