Artikel #:
0102-05
Antigen/Produkt:
NFATc1, nuclear factor of activated T-cells
Synonym(e):
NFATc1, NF-ATc, NF-ATc1, NFAT transcription complex cytosolic component, NFAT2, NFATc, Nuclear factor of activated T-cells c1, Nuclear factor of activated T-cells cytoplasmic 1
Uni-/SwissProt #:
O95644, Q12865, Q15793
Klon / Name:
IG-205
Aus Spezies:
Kaninchen
Mono-/polyklonal:
polyklonal (pAB) | anti-Teilsequenz
Reinheit:
affinitätsgereinigt am Antigen
Menge (Masse):
50 µg
Menge (Vol.):
100 µl
Preis (netto):
215.00 €
Reaktion mit Spezies:
Mensch
Anwendungen:
WB - Western Blot / Immunoblot, IF - Immunfluoreszenz, IHC - Immun-Histochemie, IP - Immunpräzipitation, ChIP - Chromatin-Immunpräzipitation
Verdünnungen:
WB: (1:500-1:1,000); IP: (1:200), band shift assays
Bemerkungen:
Kompetitiert mit der Sonde um die NFAT-Bindungin Band Shift Assays.
Form:
steril filtrierte Lösung, mit Na-Azid, stabilisiert mit Träger(protein)
Immunisierung:
rekombinantes Protein (Teilsequenz)
Epitop:
N-terminale Hälfte des Proteins
Lagerung:
-20°C
Versand:
Kühlpaket
Verfügbarkeit:
vorrätig
Datenblatt:
Publikationen, die dieses Produkt verwenden:
1.
Patra, A. K. et al. An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development. Nat Immunol 14, 127–135 (2013). (Article).
2.
Hock, M. et al. NFATc1 induction in peripheral T and B lymphocytes. J. Immunol. 190, 2345–2353 (2013). (Article).
3.
Bhattacharyya, S. et al. NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network. J. Exp. Med. 208, 823–839 (2011). (Article).
4.
Nayak, A. et al. Sumoylation of the Transcription Factor NFATc1 Leads to Its Subnuclear Relocalization and Interleukin-2 Repression by Histone Deacetylase. J. Biol. Chem. 284, 10935–10946 (2009). (Article).
5.
Silbermann, K., Schneider, G. & Grassmann, R. Stimulation of interleukin-13 expression by human T-cell leukemia virus type 1 oncoprotein Tax via a dually active promoter element responsive to NF-κB and NFAT. J Gen Virol 89, 2788–2798 (2008). (Article).
6.
Klein-Hessling, S. et al. Cyclic AMP-induced Chromatin Changes Support the NFATc-mediated Recruitment of GATA-3 to the Interleukin 5 Promoter. J. Biol. Chem. 283, 31030–31037 (2008). (Article).
7.
Akimzhanov, A. et al. Epigenetic Changes and Suppression of the Nuclear Factor of Activated T Cell 1 (NFATC1) Promoter in Human Lymphomas with Defects in Immunoreceptor Signaling. Am J Pathol 172, 215–224 (2008). (Article).
8.
Klein, M. et al. Specific and Redundant Roles for NFAT Transcription Factors in the Expression of Mast Cell-Derived Cytokines. J Immunol 177, 6667–6674 (2006). (Article).
9.
Glazova, M. et al. Pim-1 kinase enhances NFATc activity and neuroendocrine functions in PC12 cells. Brain Res. Mol. Brain Res. 138, 116–123 (2005). (Article).
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